PhD or equivalent in biology or related field/9 years

Molecular Biology RESEARCH: Cell culture, animal work, western blot, qPCR, IHC, ELISA

N/A

Sitting at computer work station for long periods of time

Standing for long periods of time

Risk of back injury from moving/lifting, equipment, or materials

Repetitive motion

Lifting/Carrying up to _25____lbs.

Pushing/Pulling up to ____25___ lbs.

Job Related Travel

Loud Noises

Hazardous Chemicals or fumes

Temperature extremes

Radiation

Burns/Cuts/Punctures

Bloodborne/Airborne Pathogens/Recombinant DNA/Viral Vectors

Monday Friday 8a-5p, occasional overtime, some weekends required

The Markey Cancer Center is seeking a Post-Doctoral Scholar. We have established the importance of neurotensin (NTS), a gut hormone peptide, in obese development and its associated metabolic disorders. Obesity is associated with an increase in colorectal cancer (CRC) incidence. We also found that NTS regulates intestinal epithelial cells as well as intestinal stem cells (ISC) in a manner dependent on the availability of nutrients. Under nutrient-rich conditions, NTS promotes crypt cell proliferation. Under conditions of nutrient depletion, NTS enhances ISC function. Obesity may rise intestinal carcinogenesis by increasing Intestinal ISC/progenitor's population, stemness, and niche. We will investigate whether NTS regulates CRC carcinogenesis via ISC or their niche. The new postdoc. will perform the in vitro experiments including cell culture, western blot, qPCR, IHC or ELISA. He/or she will perform intestinal crypt isolation and 3D organoid culture, tumor spheroid culture from mice and patients. He/or she will also work with mice, such as sacrificing mice and collecting tissues.

This position will have a fully on-site work arrangement.

IMPORTANT: Resumes and CVs cannot be substituted for a completed application. Incomplete applications could disqualify you from being considered for this position. If the information on your resume is not entered on the application, this will prevent us from being able to assess your education and experience when trying to determine a salary offer. To be considered you must fully complete the online application being sure to only put one (1) job title for each entry (multiple job titles for one employer must have separate entries), the # of hours worked per week and your ending salary. You will also be required to upload a Cover Letter, CV, PhD transcript and as specific request 1, a copy of your PhD diploma. Optionally, you can upload a writing sample.

To view our exceptional benefits, please visit https://www.uky.edu/hr/benefits.

Use software of Microsoft word, excel, powerpoint, Adobe photoshop, Endnote

Work experience in Molecular biology and signaling pathways

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